There is a whole range of newly emerging techniques that have traditionally employed laser light to illuminate a sample, but are now turning to LEDs. An example is structured illumination microscopy (SIM), a wide-field technique that can improve the lateral resolution beyond the diffraction limit by a factor of two.

This is achieved by projecting a series of patterns sequentially onto a sample and capturing images, followed by post-processing. Fast LED color switching and DMD (deformable mirror devices) for generating the pattern means high speeds can be achieved compared to the traditional mechanical method of structured pattern generation.

View more information on our pE-4000.

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